Melanotan 2 Nasal Tanning Spray Tutorial


Do not use melanotan 2 when pregnant or breast feeding.
Do not use melanotan 2 if you have pigmented mole, the melanotan 2 (MT2) will cause the moles to change shape and colour – it has been argued that the moles will return to their original form after use of MT2 has ceased. However this is not recommended, all UV exposure should be avoided with this skin condition.

It should be noted that the nasal spray method isn’t as effective as the “injection” delivery method because the nasal cavity only has a 30-50% absorption rate, therefore it will take 2-3 times as much to achieve the same results. However the melanotan 2 nasal spray is a viable method and will achieve amazing results.

side effects


·         Darkened skin

·         Increased libido

·         Weight loss

·         Darkening of moles and freckles

·         Nausea

·         Stomach cramp

·         Decreased appetite

·         Flushing

·         And other side effects.

1. Mixing (reconstitution) Of Melanotan

Please make sure that you do this in a clean environment to reduce the risk of contamination. You can add more than 1 vail to each nasal pump. A maximum of 10MGS Melanotan 2 per 1ML of saline solution/sterile water. 

Please do not confuse:
Milligrams (MGS) = solid
Millilitres (MLS) = liquid

*If you have purchased the “premixed” nasal spray skip this step and go straight to step 2

Snap of off the red plastic lid

(A) Snap of off the red plastic lid of your glass vial which contains the Melanotan 2.

Twist the top of the plastic bottle

(B) Twist the top of the plastic bottle which contains 5ML of sterile water or saline solution.

Insert the needle into the plastic bottle

(C) Insert the needle into the plastic bottle and draw back on the plunger, allow the syringe to fill to the maximum 1ML with sterile water/ saline solution.

Add 1 ml saline solutions

(D) Now add the 1ML of the mixing water till the glass vial containing melanotan 2 (the process is called reconstitution/mixing). Insert the syringe through the centre ring of the grey rubber stopper and slowly push down on the plunger. Then remove the syringe and gently and roll the vial between your index finger and thumb. Allowing the powder to dissolve into the sterile water.

transferred reconstituted solution to syringe

(E)  Now transfer the reconstituted solution till the nasal spray bottle using the syringe.

Add saline solutions


Add the rest of the mixing water till the nasal spray bottle (it should fill till the neck). See dosing and frequency for more detail.


Black leak prevention seal

(G) Ensure the black leak prevention seal in in place before reassembling the nasal kit. This additional seal will help prevent any leakage while in storage.

clear plastic cap is employed

(F) Finally, screw the lid back on to the nasal spray bottle ( ensure the clear plastic cap is employed).

Insert the top of the nasal pump into the nostril and press – For maximum results, the solution must sit on the membrane at the top of the nasal cavity. Be careful not to spray too much.

2. Dosing and frequency

Each vial contains 10 doses.

A dose depends on how much of the mixing water it was diluted with e.g.

When mixed with 5ml of saline solution/sterile water approximately 4 squirts (in total) = 1 dose.


The idea is to allow the reconstituted solution ( liquid substance ) to rest on the membrane inside the top of the nasal cavity ( see illustration ). Be careful not to “squirt” too much/high as this is not effective.

membrane - dosing and frequency


The loading phase: 
This phase is until you achieve your desired skin tone.
Take one dose per day or every other day. For optimal results (although not necessary) get UV exposure within 8 hours of dosing. Note: if you suffer with nausea associated with using melanotan dose before bed as to avoid the feeling. Don’t worry about this feeling as it will usually dissipate after around a week of use alternatively you can lower your dosage. For most people around 2-3 vials of nasal spray delivery method is enough to achieve their desired skin tone, however people with fair skin, red hair may take a lot longer.

Maintenance phase:
This phase is used to maintain your skin pigmentation. Use the same dose that you preferred during the loading phase, only with less frequency, once or twice a week is normal maintenance but some require doses less frequently.

Both phases should be done in conjunction with regular UV exposure i.e. sun bed session 1-2 times a week.

Fitzpatrick chart

A very common question is how long will it take for me to develop a deep lasting tan?

It varies from person to person and has a few determining factors, the main one being natural skin tone/tanning ability. Regardless of your natural skin tone you will still see fabulous results.

Use the Fitzpatrick skin chart determine which type you are:

melanotan nasal spray how much

Melanotan can be used to mask skin conditions such as Vitiligo, Psoriasis and Rosacea by partially or totally masking their condition.

SKin type

3. Storage.

Store in a cool dark place, away from heat and direct sunlight. 

Once the nasal spray has been reconstituted it is important that you follow these necessary precautions to prevent leakage:

  • Store in an upright position
  • Replace the clear plastic lid 
  • Do NOT take onboard aircraft (due to the pressurised cabin)
  • Do NOT store below 2°C (DO NOT store in an extremely cold fridge as the solution will evaporate

***When replacing the lid hold by the finger grips to prevent accidentally pressing the nozzle***

melanotan 2 nasal spray - mellowtan
Always hold by finger grips while replacing the lid